Mewgenics vs Slay the Spire 2

Choose Mewgenics for 200+ hours of cat-genetics depth or Slay the Spire 2 for a co-op deckbuilder with a livelier community.

Updated 27d ago

Mewgenics cover
Mewgenics 8.9/10 Strong

Makes good on the decade-long Mewgenics dev cycle — McMillen and Glaiel's cat-genetics roguelite hits Isaac territory at 89 MC and 94% recommend.

Slay the Spire 2 cover
Slay the Spire 2 8.9/10 Strong

Still the best in its genre — the new multiplayer co-op alone justifies the buy even in early access.

By the numbers

Prices checked Sep 21; they move faster than we refresh, so confirm on the store page.

Recent-review figures are Steam's own last-30-days window, read Sep 21.

Measure Mewgenics Slay the Spire 2
Value Too close to call
Price now $29.99 Steam $24.99 Steam
All-time low $22.49 $24.99
Cost / hour $0.39/hr $29.99 · 76 h main story $2.61/hr $24.99 · 10 h main story
Off its low +33% low was Jun 2026 At its low low was Mar 2026
Main story 76 h 10 h
Health Mewgenics wins on player health
Steam reviews 90% 54k reviews 61% 202k reviews
Recent reviews 86% 1k votes · vs 90% lifetime 73% 4k votes · vs 61% lifetime · improving
Peak players 5,728 Aug 2026 · ↓ 23% MoM 105,197 Aug 2026 · ↓ 16% MoM
Launch peak 5% of Feb 2026 launch peak · as of Aug 2026 18% of Mar 2026 launch peak · as of Aug 2026
All-time peak 115,063 Feb 2026 574,638 Mar 2026
Support
Last patch 2 weeks ago 6 weeks ago
Patch cadence 5 in last 90 days 5 in last 90 days
Steam Deck Platinum Platinum

Shared scale — same months across the bottom, same player-count axis up the side, so the two lines are directly comparable. A shorter line means a younger game.

Mewgenics
Feb 2026 – Aug 2026
Slay the Spire 2
Mar 2026 – Aug 2026

What players say

Patterns from long-haul reviewers, taken from each game's verdict. Not live sentiment — each side is dated below.

Mewgenics

Love

The cat-breeding loop's mutation chains and roguelike adventure variety are what 200-hour fans replay for.

Struggle with

The brutality of losing a well-bred cat line is the wall that ends many long playthroughs.

from our May 2026 verdict

Slay the Spire 2

Love

The new four-player co-op hooks even skeptical friends, and regular updates keep the card pool evolving

Struggle with

Ascension 10 balancing draws consistent frustration — brutal enemy scaling and RNG-heavy bosses feel unfair to many

from our August 2026 verdict

Key differences

Content depth
Mewgenics spans 76 main-story hours and a meta progression that supports 200+ hour run cycles.
Slay the Spire 2's main story wraps in 10 hours, with most playtime driven by co-op and balance patches.
Multiplayer focus
Mewgenics is a solo affair, leaning on its genetics system and Isaac-like humor.
Slay the Spire 2's new co-op mode is the headline feature, making it a stronger pick for groups.
Community vitality
Mewgenics' monthly peak is only 6% of launch, indicating a quieter player base.
Slay the Spire 2 retains 22% of its launch peak, suggesting a more active community.

Which one is for you?

Pick Mewgenics if

  • You loved Binding of Isaac and want a turn-based twist
  • You're fine with a 200+ hour meta grind and no co-op
  • You're a fan of McMillen's edgy aesthetic and humor

Pick Slay the Spire 2 if

  • You want co-op deck-building with friends now
  • You prefer a shorter, self-contained run over long-term grinding
  • You like engaging with frequent balance updates and dev feedback

Bottom line

Mewgenics is the pick for solo players who want Isaac-style depth and can invest 76+ hours; choose Slay the Spire 2 if you play with friends or want a lively community at 22% of its peak.

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